Donders Institute for Brain, Cognition and Behaviour · Radboud University
Neuroscientist
Oscillations synchronise into large-scale patterns that hover at the edge of criticality, ordered enough to sustain function, flexible enough to be perturbed. My research explores the dynamical principles that govern this balance and how perturbations can reshape it.
My research is driven by a simple question: how do billions of interacting neurons give rise to coherent thought, perception and behaviour? Rather than viewing the brain as a collection of specialised regions, I approach it as a complex dynamical system, where large-scale patterns emerge from the interactions of countless oscillations. My work seeks to uncover the principles that govern these dynamics, how they remain both stable and adaptable, and how carefully designed perturbations can reveal the mechanisms that organise the system. By combining mathematical modelling with experimental neuromodulation, I aim to bridge theory and experiment in the study of large-scale brain dynamics.
Complex behaviour emerges from remarkably simple rules. Mathematical and computational models provide a framework for understanding how local interactions give rise to large-scale brain dynamics, and for generating mechanistic hypotheses about the principles that govern them.
Theories must ultimately explain the brain we can observe. Electrophysiology captures the rich repertoire of neural dynamics across space and time, allowing theoretical predictions to be tested against the behaviour of real biological systems.
Perturbation reveals what observation alone cannot. By introducing controlled perturbations to neural activity, neuromodulation provides a way to probe the mechanisms governing large-scale brain dynamics and to test theoretical predictions of how the system responds.
eBRAIN-Health (Horizon Europe, 101058516) — development of BrainX3, an interactive platform for visualising and exploring multimodal brain data and whole-brain simulations.
AISN — Artificial Intelligence in Stroke Neurorehabilitation (Horizon Europe, 101057655) — dynamical EEG biomarkers of stroke recovery for predicting motor outcomes.
TVB-Cloud — The Virtual Brain Cloud (Horizon 2020, 826421) — cloud-based Virtual Research Environment for large-scale brain modelling within the EBRAINS ecosystem.
Dynamical systems · Whole-brain modelling · Neural dynamics
EEG / MEG analysis · Spectral analysis · Signal processing
MRI processing · Image-guided stimulation planning
Transcranial ultrasound stimulation (TUS) · Stimulation protocols
Python · MATLAB · R · Linux · LaTeX